Background:

This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl- exit in NaCl absorbing epithelia.

Applications:

ELISA, IHC

Name of antibody:

SLC12A4

Immunogen:

Fusion protein of human SLC12A4

Full name:

solute carrier family 12 (potassium/chloride transporters), member 4

Synonyms：

KCC1

SwissProt:

Q9UP95

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human colon cancer

IHC Recommend dilution:

50-200