Background:

This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Applications:

ELISA, WB, IHC

Name of antibody:

PIP5K1C

Immunogen:

Synthetic peptide of human PIP5K1C

Full name:

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma

Synonyms：

LCCS3; PIPKIg_v4; PIP5Kgamma; PIP5K-GAMMA

SwissProt:

O60331

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human brain

IHC Recommend dilution:

25-100

WB Predicted band size:

73 kDa

WB Positive control:

A431 and hela cells

WB Recommended dilution:

500-2000