Background:

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Applications:

ELISA, WB

Name of antibody:

NFATC4

Immunogen:

Synthetic peptide of human NFATC4

Full name:

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

Synonyms：

NFAT3; NF-ATc4

SwissProt:

Q14934

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

102 kDa

WB Positive control:

NIH/3T3 and Jurkat cells

WB Recommended dilution:

500-2000