Background:

The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Applications:

ELISA, WB

Name of antibody:

MAP4K2

Immunogen:

Fusion protein of human MAP4K2

Full name:

mitogen-activated protein kinase kinase kinase kinase 2

Synonyms：

GCK; BL44; RAB8IP

SwissProt:

Q12851

ELISA Recommended dilution:

2000-10000

WB Predicted band size:

92 kDa

WB Positive control:

Human fetal brain tissue

WB Recommended dilution:

1000-5000