Background:

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

PAK1

Immunogen:

Synthetic peptide of human PAK1

Full name:

P21 protein (Cdc42/Rac)-activated kinase 1

Synonyms：

PAKalpha

SwissProt:

Q13153

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human liver cancer and Human colon cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

61 kDa

WB Positive control:

293T and K562 cells

WB Recommended dilution:

500-2000