Background:

Prostaglandin E synthase 3 (cytosolic) is an enzyme that in humans is encoded by the PTGES3 gene. The protein encoded by this gene is also known as p23 which functions as a chaperone which is required for proper functioning of the glucocorticoid and other steroid receptors. Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.

Applications:

ELISA, IHC

Name of antibody:

PTGES3

Immunogen:

Fusion protein of human PTGES3

Full name:

prostaglandin E synthase 3 (cytosolic)

Synonyms：

P23; TEBP; cPGES

SwissProt:

Q15185

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and human thyroid cancer

IHC Recommend dilution:

25-100